Feasibility study of using unbalanced embryos as a reference to distinguish euploid carrier from noncarrier embryos by single nucleotide polymorphism array for reciprocal translocations.

Abstract excerpt

OBJECTIVES: To study the feasibility of using unbalanced embryos as a reference in distinguishing euploid carrier and noncarrier embryos by single nucleotide polymorphism (SNP) array-based preimplantation genetic testing (PGT) for reciprocal translocations. METHODS: After comprehensive chromosome screening (CCS), euploid embryos were identified as normal or carriers using a family member as a reference. Next,...

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