Article
Single nucleotide polymorphism microarray-based concurrent screening of 24-chromosome aneuploidy and unbalanced translocations in preimplantation human embryos.
Fertility and sterility - 1 Apr 2011
Treff Nathan R, Northrop Lesley E, Kasabwala Khushabu, Su Jing, Levy Brynn, Scott Richard T
Abstract excerpt
OBJECTIVE: To develop, validate, and apply a single nucleotide polymorphism (SNP) microarray-based method for simultaneous preimplantation genetic diagnosis (PGD) of unbalanced inheritance of rearranged chromosomes and 24-chromosome aneuploidy screening. DESIGN: Prospective clinical research study. SETTING: Academic reproductive medicine center. PATIENT(S): Eighteen couples carrying a balanced reciprocal or...
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