Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity, and Insulin Resistance.

doi:10.2337/db20-0096

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Article

Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity, and Insulin Resistance.

Diabetes - 1 Mar 2021

Jersin Regine Å, Tallapragada Divya Sri Priyanka, Madsen André, Skartveit Linn, Fjære Even, McCann Adrian, Lawrence-Archer Laurence, Willems Aron, Bjune Jan-Inge, Bjune Mona S, Våge Villy, Nielsen Hans Jørgen, Thorsen Håvard Luong, Nedrebø Bjørn Gunnar, Busch Christian, Steen Vidar M, Blüher Matthias, Jacobson Peter, Svensson Per-Arne, Fernø Johan, Rydén Mikael, Arner Peter, Nygård Ottar, Claussnitzer Melina, Ellingsen Ståle, Madsen Lise, Sagen Jørn V, Mellgren Gunnar, Dankel Simon N

Abstract excerpt

Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance may lead to improved therapeutic options for type 2 diabetes and other obesity-related diseases. Here, we find that adipose expression of the small neutral amino acid transporter SLC7A10, also known as alanine-serine-cysteine transporter-1 (ASC-1), shows strong inverse correlates with visceral adiposity, insulin...

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PMID: 33408126
DOI: 10.2337/db20-0096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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