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Pro-Oncogenic and Anti-Oncogenic Pathways: Opportunities and Challenges of Cancer Therapy

7 Apr 2010

Abstract excerpt

Carcinogenesis is the uncontrolled growth of cells gaining the potential to invade and disrupt vital tissue functions. This malignant process includes the occurrence of 'unwanted' gene mutations that induce the transformation of normal cells, for example, by overactivation of pro-oncogenic pathways and inactivation of tumor-suppressive or anti-oncogenic pathways. It is now recognized that the number of major...

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PMID: 20373871
DOI: 10.2217/fon.10.15

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