Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Exploring the Genetic Orchestra of Cancer: The Interplay Between Oncogenes and Tumor-Suppressor Genes

24 Mar 2025

Abstract excerpt

Cancer is complex because of the critical imbalance in genetic regulation as characterized by both the overexpression of oncogenes (OGs), mainly through mutations, amplifications, and translocations, and the inactivation of tumor-suppressor genes (TSGs), which entail the preservation of genomic integrity by inducing apoptosis to counter the malignant growth. Reviewing the intricate molecular interplay between OGs...

Source

Identifiers

PMID: 40227591
DOI: 10.3390/cancers17071082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring the Genetic Orchestra of Cancer: The Interplay Between Oncogenes and Tumor-Suppressor GenesPMID 40227591Read ↗

Translational Advances in Oncogene and Tumor-Suppressor Gene ResearchSemantic proximity Read ↗

Genetic landscape of cancer: mechanisms, key genes, and therapeutic implications.Semantic proximity Read ↗

Multidimensional effects of genetic mechanisms in cancer occurrence, development and treatment.Semantic proximity Read ↗

Precision Oncology, Signaling Pathways Reprogramming and Targeted Therapy: A Holistic Approach to Molecular Cancer TherapeuticsSemantic proximity Read ↗

Targeting Oncogenic Pathways in the Era of Personalized Oncology: A Systemic Analysis Reveals Highly Mutated Signaling Pathways in Cancer Patients and Potential Therapeutic TargetsSemantic proximity Read ↗

Molecular principles underlying aggressive cancersSemantic proximity Read ↗

Precision Oncology, Signaling Pathways Reprogramming and Targeted Therapy: A Holistic Approach to Molecular Cancer TherapeuticSemantic proximity Read ↗

Precision Oncology, Signaling Pathways Reprogramming and Targeted Therapy: A Holistic Approach to Molecular Cancer TherapeuticSemantic proximity Read ↗

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.Semantic proximity Read ↗

Precision Oncology, Signaling Pathways Reprogramming and Targeted Therapy: A Holistic Approach to Molecular Cancer TherapeuticsSemantic proximity Read ↗

Advancements in Cancer TreatmentsSemantic proximity Read ↗

Precision Oncology-Based Targeting of Signaling Pathways toward a Holistic Approach to Cancer TherapeuticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.