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Article

Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa.

Molecular psychiatry - 1 Apr 2016

Shih P B, Yang J, Morisseau C, German J B, Zeeland A A Scott-Van, Armando A M, Quehenberger O, Bergen A W, Magistretti P, Berrettini W, Halmi K A, Schork N, Hammock B D, Kaye W

Abstract excerpt

Individuals with anorexia nervosa (AN) restrict eating and become emaciated. They tend to have an aversion to foods rich in fat. Because epoxide hydrolase 2 (EPHX2) was identified as a novel AN susceptibility gene, and because its protein product, soluble epoxide hydrolase (sEH), converts bioactive epoxides of polyunsaturated fatty acid (PUFA) to the corresponding diols, lipidomic and metabolomic targets of EPHX2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25824304
DOI: 10.1038/mp.2015.26
PMCID: PMC4591075

Genes

EPHX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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