Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decoding the Genetic Alterations in Genes of DNMT Family (DNA Methyl-Transferase) and their Association with Head and Neck Squamous Cell Carcinoma.

Asian Pacific journal of cancer prevention : APJCP - 1 Dec 2020

Fathima Tahreem, Arumugam Paramasivam, Girija As Smiline, Priyadharsini J Vijayashree

Abstract excerpt

OBJECTIVE: Epigenetic modifications are gaining focus due to their indirect association with tumorigenesis. DNA methylation plays a prime role in regulation of gene expression. Any aberrations in this gene family may lead to chromosomal instability and increased magnitude of tumour progression. In line with the above fact, the present study has been designed to identify genetic alterations in the genes of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA (Cytosine-5-)-Methyltransferases
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Follow-Up Studies

Share to Gene Expression Regulation, Neoplastic

Share to Head and Neck Neoplasms

Share to Squamous Cell Carcinoma of Head and Neck

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 33369458
DOI: 10.31557/APJCP.2020.21.12.3605
PMCID: PMC8046301

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decoding the Genetic Alterations in Genes of DNMT Family (DNA Methyl-Transferase) and their Association with Head and Neck Squamous Cell Carcinoma.PMID 33369458Read ↗

Bioinformatics analysis of DNMT1 expression and its role in head and neck squamous cell carcinoma prognosis.Semantic proximity Read ↗

The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

The Role of the DNA Methyltransferase Family and the Therapeutic Potential of DNMT Inhibitors in Tumor TreatmentSemantic proximity Read ↗

A novel C/T polymorphism in the core promoter of human de novo cytosine DNA methyltransferase 3B6 is associated with prognosis in head and neck cancer.Semantic proximity Read ↗

De novo DNMTs and DNA methylation: novel insights into disease pathogenesis and therapy from epigenomics.Semantic proximity Read ↗

Portrait of DNA methylated genes predictive of poor prognosis in head and neck cancer and the implication for targeted therapy.Semantic proximity Read ↗

Analysis of the Oncogenic Role of Methyltransferase Like 3 (METLL3) in Head and Neck Squamous Cell Carcinoma (HNSCC)Semantic proximity Read ↗

A Clinically Distinct and 'Atypical' Subgroup of Head and Neck Cancers Positive for a CpG Island Methylator Phenotype.Semantic proximity Read ↗

Alterations to DNMT3A in Hematologic Malignancies.Semantic proximity Read ↗

Profiling genetic mutations in the DNA damage repair genes of oral squamous cell carcinoma patients from PakistanSemantic proximity Read ↗

Analysis of Genomic DNA Methylation and Gene Transcription Modulation Induced by DNMT3A Deficiency in HEK293 CellsSemantic proximity Read ↗

AML-Associated Mutations in DNA Methyltransferase DNMT3A.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.