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Article

Polymorphisms in mitochondrial ribosomal protein S5 (MRPS5) are associated with leprosy risk in Chinese.

PLoS neglected tropical diseases - 1 Dec 2020

Xing Yan, He Jun, Wen Yan, Liu Jian, You Yuangang, Weng Xiaoman, Yuan Lianchao, Xiong Li, Chen Xiaohua, Zhang Ying, Li Huan-Ying

Abstract excerpt

Leprosy is an infectious disease caused by Mycobacterium leprae (M. leprae), with about 210,000 new cases per year worldwide. Although numerous risk loci have been uncovered by genome-wide association studies, the effects of common genetic variants are relatively modest. To identify possible new genetic locus involved in susceptibility to leprosy, whole exome sequencing was performed for 28 subjects including 14...

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Identifiers

PMID: 33362202
DOI: 10.1371/journal.pntd.0008883
PMCID: PMC7757804

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