Article
The loss-of-function mutation of CETP affects HDLc levels but not ApoA1 in patients with acute myocardial infarction.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 8 Feb 2021
Li Weiping, Liu Xin, Huang Chunyi, Liu Liusheng, Tan Xuerui, Wang Xingyu
Abstract excerpt
BACKGROUND AND AIMS: Loss of the cholesteryl ester transfer protein (CETP) function affects HDLc levels, but its effects on major HDL protein component ApoA1 are not well understood in patients with acute myocardial infarction (AMI). METHODS AND RESULTS: We investigated the effects of an East Asian loss-of-function variant (rs2303790; p.D442G) in CETP gene on HDLc and ApoA1 levels and its relationship with AMI. A...
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