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Article

Imaging Cancer-Associated Fibroblasts (CAFs) with FAPi PET

2022-01-21

Abstract excerpt

The tumor microenvironment (TME) surrounding tumor cells is a complex and highly dynamic system that promotes tumorigenesis. Cancer-associated fibroblasts (CAFs) are key elements in TME playing a pivotal role in cancer cells’ proliferation and metastatic spreading. Considering the high expression of the fibroblast activation protein (FAP) on cell membrane, CAFs emerged as appealing TME targets, namely for molecula...

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Literature Corpus work
4b964195-1af3-5a94-a0ab-925df73fca57
DOI
10.20944/preprints202201.0327.v1
Open publication

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