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Article

TH17/IL23 cytokine gene polymorphisms in bullous pemphigoid.

Molecular genetics & genomic medicine - 1 Dec 2020

Tabatabaei-Panah Pardis-Sadat, Moravvej Hamideh, Aghaei Sahel, Akbari Maryam, Rajabi Sakineh, Kia Atena, Ebrahimi Elaheh, Sadaf Zahra, Atoon Alireza, Behravesh Nasim, Ludwig Ralf J, Akbarzadeh Reza

Abstract excerpt

BACKGROUND: TH17/IL-23 immune axis is considered to be involved in the pathogenesis of autoimmune and chronic inflammatory diseases. Bullous pemphigoid (BP) is the most frequent autoimmune blistering disease, characterized by the presence of autoantibodies against the components of the dermal-epidermal junction. Animal studies and characterization of patient samples point toward a contribution of TH17 cells in BP...

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Identifiers

PMID: 33340282
DOI: 10.1002/mgg3.1519
PMCID: PMC7767565

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