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Article

Association between TH2 Cytokine Gene Polymorphisms and Risk of Bullous Pemphigoid.

Immunological investigations - 1 Feb 2022

Tabatabaei-Panah Pardis-Sadat, Moravvej Hamideh, Alirajab Marzieh, Etaaty Ahmad, Geranmayeh Maryam, Hosseine Farzaneh, Khansari Atousa, Mahdian Mohadeseh, Mirhashemi Mahsa, Parvizi Samira, Sakhaie Fatemeh, Ludwig Ralf J, Akbarzadeh Reza

Abstract excerpt

BACKGROUND: T-helper 2 (Th2)-associated cytokines are involved in the pathogenesis of bullous pemphigoid (BP), an autoimmune skin disease. Increased expression of Th2 cytokines such as interleukin-4 (IL-4), IL-5, IL-6, IL-10, and IL-13 have been observed in serum, skin biopsies and/or blister fluid. This study aimed to uncover a possible association between Th2 cytokine genetic variations and susceptibility to...

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Identifiers

PMID: 33047635
DOI: 10.1080/08820139.2020.1832113

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