Article
Cytokine gene polymorphisms in bullous pemphigoid in a Chinese population.
The British journal of dermatology - 1 Jan 2006
Chang Y T, Liu H N, Yu C W, Lin M W, Huang C H, Chen C C, Liu M T, Lee D D, Wang W J, Tsai S F
Abstract excerpt
BACKGROUND: Bullous pemphigoid (BP) is an autoimmune bullous disease mostly associated with autoantibodies to the hemidesmosomal BP autoantigens BP180 and BP230. High levels of interleukin (IL)-1beta, IL-4, IL-5, IL-6, IL-8, IL-10, IL-13, tumour necrosis factor (TNF)-alpha and interferon (IFN)-gamma have been detected in skin lesions or sera of patients with BP. Cytokine gene polymorphisms may affect cytokine...
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