Article
Surgical ablation of whitened interscapular brown fat ameliorates cardiac pathology in salt-loaded metabolic syndrome rats.
Annals of the New York Academy of Sciences - 1 May 2021
Komatsu Yuki, Aoyama Kiyoshi, Yoneda Mamoru, Ito Shogo, Sano Yusuke, Kawai Yumeno, Cui Xixi, Yamada Yuichiro, Furukawa Nozomi, Ikeda Katsuhide, Nagata Kohzo
Abstract excerpt
Brown adipose tissue (BAT) is an endocrine organ that contributes to thermogenesis and energy consumption. We investigated the effects of salt loading and surgical removal of whitened interscapular BAT (iBAT) on cardiac and adipose tissue pathology in DahlS.Z-Leprfa /Leprfa (DS/obese) rats, an animal model of metabolic syndrome (MetS). DS/obese rats were subjected to surgical removal of iBAT or sham surgery at 8...
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