Article
Systematic evaluation of the effects of genetic variants on PIWI-interacting RNA expression across 33 cancer types.
Nucleic acids research - 11 Jan 2021
Xin Junyi, Du Mulong, Jiang Xia, Wu Yanling, Ben Shuai, Zheng Rui, Chu Haiyan, Li Shuwei, Zhang Zhengdong, Wang Meilin
Abstract excerpt
PIWI-interacting RNAs (piRNAs) are an emerging class of non-coding RNAs involved in tumorigenesis. Expression quantitative trait locus (eQTL) analysis has been demonstrated to help reveal the genetic mechanism of single nucleotide polymorphisms (SNPs) in cancer etiology. However, there are no databases that have been constructed to provide an eQTL analysis between SNPs and piRNA expression. In this study, we...
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