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Article

iPiDi-PUL: identifying Piwi-interacting RNA-disease associations based on positive unlabeled learning.

Briefings in bioinformatics - 20 May 2021

Wei Hang, Xu Yong, Liu Bin

Abstract excerpt

Accumulated researches have revealed that Piwi-interacting RNAs (piRNAs) are regulating the development of germ and stem cells, and they are closely associated with the progression of many diseases. As the number of the detected piRNAs is increasing rapidly, it is important to computationally identify new piRNA-disease associations with low cost and provide candidate piRNA targets for disease treatment. However,...

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PMID: 32393982
DOI: 10.1093/bib/bbaa058

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