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Article

Genetic variants in noncoding PIWI-interacting RNA and colorectal cancer risk.

Cancer - 15 Jun 2015

Chu Haiyan, Xia Liping, Qiu Xiaonan, Gu Dongying, Zhu Linjun, Jin Jing, Hui Gaoyun, Hua Qiuhan, Du Mulong, Tong Na, Chen Jinfei, Zhang Zhengdong, Wang Meilin

Abstract excerpt

BACKGROUND: PIWI-interacting RNAs (piRNAs), which are a novel type of identified small noncoding RNA (ncRNA), play a crucial role in germline development and carcinogenesis. METHODS: By systematically screening all known piRNAs, the authors identified 7 common single nucleotide polymorphisms (SNPs) in 9 piRNAs. Associations between these selected SNPs and the risk of colorectal cancer (CRC) were detected in a...

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PMID: 25740697
DOI: 10.1002/cncr.29314

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