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Article

NCOA3 identified as a new candidate to explain autosomal dominant progressive hearing loss.

Human molecular genetics - 21 Jan 2021

Salazar-Silva Rodrigo, Dantas Vitor Lima Goes, Alves Leandro Ucela, Batissoco Ana Carla, Oiticica Jeanne, Lawrence Elizabeth A, Kawafi Abdelwahab, Yang Yushi, Nicastro Fernanda Stávale, Novaes Beatriz Caiuby, Hammond Chrissy, Kague Erika, Mingroni-Netto Regina Célia

Abstract excerpt

Hearing loss is a frequent sensory impairment in humans and genetic factors account for an elevated fraction of the cases. We have investigated a large family of five generations, with 15 reported individuals presenting non-syndromic, sensorineural, bilateral and progressive hearing loss, segregating as an autosomal dominant condition. Linkage analysis, using SNP-array and selected microsatellites, identified a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Developmental

Share to Hair Cells, Auditory

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Identifiers

PMID: 33326993
DOI: 10.1093/hmg/ddaa240
PMCID: PMC7823111

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