Otosclerosis.

doi:10.1159/000322488

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Article

Otosclerosis.

Advances in oto-rhino-laryngology - 1 Jan 2011

Ealy Megan, Smith Richard J H

Abstract excerpt

Otosclerosis is one of the more common forms of adult-onset hearing loss with a prevalence of 0.3-0.4% in Caucasians. It is typically characterized by a conductive hearing loss due to labyrinthine endochondral sclerosis that upon stapedio-vestibular joint invasion results in loss of free motion of the stapes. Its etiology remains poorly understood with both environmental factors and genetic causes implicated in...

Topics

Gene Expression
Genetic Linkage
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Otosclerosis
Prevalence
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 21358194
DOI: 10.1159/000322488

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