Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage of otosclerosis to a third locus (OTSC3) on human chromosome 6p21.3-22.3

1 Jul 2002

Abstract excerpt

Clinical otosclerosis (OMIM 166800/605727) has a prevalence of 0.2-1% among white adults, making it the single most common cause of hearing impairment in this group. It is caused by abnormal bone homeostasis of the otic capsule with the consequent development of sclerotic foci that invade the stapedio-vestibular joint (oval window) interfering with free motion of the stapes. Impaired ossicular chain mobility...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital Ear and Nasal Anomalies
Share to Ear Surgery and Otitis Media
Share to Hearing, Cochlea, Tinnitus, Genetics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12114476
DOI: 10.1136/jmg.39.7.473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage of otosclerosis to a third locus (OTSC3) on human chromosome 6p21.3-22.3PMID 12114476Read ↗

A second gene for otosclerosis, OTSC2, maps to chromosome 7q34-36.Semantic proximity Read ↗

Otosclerosis.Semantic proximity Read ↗

Chromosomal mapping and phenotypic characterization of hereditary otosclerosis linked to the OTSC4 locus.Semantic proximity Read ↗

A new locus for otosclerosis, OTSC8, maps to the pericentromeric region of chromosome 9.Semantic proximity Read ↗

A review on the genetics of otosclerosis.Semantic proximity Read ↗

Phenotype description of a Dutch otosclerosis family with suggestive linkage to OTSC7.Semantic proximity Read ↗

The genetics of otosclerosis.Semantic proximity Read ↗

Otosclerosis: exclusion of linkage to the OTSC1 and OTSC2 loci in four Italian families.Semantic proximity Read ↗

A pathogenic deletion in Forkhead Box L1 (FOXL1) identifies the first otosclerosis (OTSC) geneSemantic proximity Read ↗

Localization of a gene for otosclerosis to chromosome 15q25-q26Semantic proximity Read ↗

Genetics of OtosclerosisSemantic proximity Read ↗

A Pathogenic Deletion in Forkhead Box L1 (FOXL1) Identifies the First Otosclerosis (OTSC) GeneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.