Article
3p-- syndrome defines a hearing loss locus in 3p25.3.
Hearing research - 1 Feb 2007
McCullough Brendan J, Adams Joe C, Shilling Dustin J, Feeney M Patrick, Sie Kathleen C Y, Tempel Bruce L
Abstract excerpt
Deletions affecting the terminal end of chromosome 3p result in a characteristic set of clinical features termed 3p-- syndrome. Bilateral, sensorineural hearing loss (SNHL) has been found in some but not all cases, suggesting the possibility that it is due to loss of a critical gene in band 3p25. To date, no genetic locus in this region has been shown to cause human hearing loss. However, the ATP2B2 gene is...
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