Article
Targeted Molecular Sequencing of Recurrent and Multifocal Non-HPV-associated Squamous Cell Carcinoma of the Vulva.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2021
Pors Jennifer, Tessier-Cloutier Basile, Thompson Emily, Almadani Noorah, Ho Julie, Gilks Blake, Huntsman David, Hoang Lynn
Abstract excerpt
Recurrent vulvar squamous cell carcinomas (SCCs) are a poorly understood and aggressive group of treatment-resistant neoplasms. Currently, it remains unclear whether these are in fact recurrences of the same primary tumor, or the development of entirely new tumors. Here, to address this question, we examined the mutational profile of a series of patients with recurrent or multifocal non-human papilloma virus...
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