Article
Development of a dual-fluorescence reporter system for high-throughput screening of L-aspartate-α-decarboxylase.
Acta biochimica et biophysica Sinica - 29 Dec 2020
Fei Mingyue, Mao Xudan, Chen Yiyang, Lu Yalan, Wang Lin, Yang Jie, Qiu Juanping, Sun Dongchang
Abstract excerpt
β-Alanine (3-aminopropionic acid) holds great potential in industrial application. It can be obtained through a chemical synthesis route, which is hazardous to the environment. It is well known that l-aspartate-α-decarboxylase (ADC) can convert l-aspartate to β-alanine in bacteria. However, due to the low activity of ADC, industrial production of β-alanine through the green biological route remains unclear. Thus,...
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