Article
Reversible Regulation of Succinate Dehydrogenase by Tools of Photopharmacology.
Journal of agricultural and food chemistry - 13 Apr 2022
Fu Wen, Shao Zhongli, Sun Xujuan, Zhou Cong, Xu Zhiping, Zhang Yang, Cheng Jiagao, Li Zhong, Shao Xusheng
Abstract excerpt
Succinate dehydrogenase (SDH) is extremely important in metabolic function and biological processes. Modulation of SDH has been reported to be a promising therapeutic target to SDH mutations. Current measures for the regulation of SDH are scarce, and precise and reversible modulation of SDH still remains challenging. Herein, a powerful tool for reversible optical control of SDH was proposed and evaluated...
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