Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PKC signaling in glioblastoma

25 Mar 2013

Abstract excerpt

Glioblastoma Multiforme (GBM) is the most aggressive brain tumor characterized by intratumoral heterogeneity at cytopathological, genomic and transcriptional levels. Despite the efforts to develop new therapeutic strategies the median survival of GBM patients is 12-14 months. Results from large-scale gene expression profile studies confirmed that the genetic alterations in GBM affect pathways controlling cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Glioma Diagnosis and Treatment
Share to Melanoma and MAPK Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23358475
DOI: 10.4161/cbt.23615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PKC signaling in glioblastomaPMID 23358475Read ↗

The complexities of PKCα signaling in cancer.Semantic proximity Read ↗

Receptor Tyrosine Kinase Signaling and Targeting in Glioblastoma MultiformeSemantic proximity Read ↗

Identification of the potential oncogenes in glioblastoma based on bioinformatic analysis and elucidation of the underlying mechanismsSemantic proximity Read ↗

Deregulated Signaling Pathways in Glioblastoma Multiforme: Molecular Mechanisms and Therapeutic TargetsSemantic proximity Read ↗

PI3Kinase signaling in glioblastoma.Semantic proximity Read ↗

Survival kinase genes present prognostic significance in glioblastomaSemantic proximity Read ↗

Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies.Semantic proximity Read ↗

Polo-like kinases as potential targets and PLK2 as a novel biomarker for the prognosis of human glioblastomaSemantic proximity Read ↗

Protein kinase C zeta isoform is critical for proliferation in human glioblastoma cell lines.Semantic proximity Read ↗

Spatially resolved single-cell analysis uncovers protein kinase Cδ-expressing microglia with anti-tumor activity in glioblastomaSemantic proximity Read ↗

The Emerging Function of PKCtheta in CancerSemantic proximity Read ↗

Comprehensive Analysis Reveals Promising Immune Target and Prognostic Value of PLK3 in GliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.