Clinicopathologic and Molecular Analysis of Traditional Serrated Adenoma and Its Possible Precursor Lesions With Special Reference to RSPO Fusion Status : A Large Case Series From Single Institution.

doi:10.1097/PAS.0000000000002586

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clinicopathologic and Molecular Analysis of Traditional Serrated Adenoma and Its Possible Precursor Lesions With Special Reference to RSPO Fusion Status : A Large Case Series From Single Institution.

The American journal of surgical pathology - 1 Oct 2026

Kadomatsu Yuichiro, Saito Tsuyoshi, Kamba Eiji, Murakami Takashi, Yao Takashi

Abstract excerpt

Colorectal serrated lesions are divided into hyperplastic polyps (HP), sessile serrated lesions (SSL), and traditional serrated adenomas (TSA) in the sixth edition of the WHO classification. In 2018, superficially serrated adenoma (SuSA) was proposed as a new subtype of colorectal serrated lesions and a possible precursor of traditional serrated adenoma (TSA). However, tumorigenesis in the serrated pathway...

Read the complete abstract on PubMed

Topics

Humans
Adenoma
Thrombospondins
Proto-Oncogene Proteins B-raf
R-Spondins
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Aged

Mutation

Female

Male

Proto-Oncogene Proteins p21(ras)

Colorectal Neoplasms

Biomarkers, Tumor

Colonic Polyps

DNA Mutational Analysis

Gene Fusion

Adult

Precancerous Conditions

Source

Open in PubMed

Identifiers

PMID: 42393851
DOI: 10.1097/PAS.0000000000002586

Genes

HP
KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathologic and Molecular Analysis of Traditional Serrated Adenoma and Its Possible Precursor Lesions With Special Reference to RSPO Fusion Status : A Large Case Series From Single Institution.PMID 42393851Read ↗

Clinicopathological characteristics of serrated polyps as precursors to colorectal cancer: Current status and management.Semantic proximity Read ↗

Colorectal serrated pathway cancers and precursorsSemantic proximity Read ↗

[Superficial serrated adenoma: a clinicopathological analysis of ten cases].Semantic proximity Read ↗

The spectrum of serrated colorectal lesions-new entities and unanswered questions.Semantic proximity Read ↗

Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression.Semantic proximity Read ↗

Clinicopathological and molecular correlations in traditional serrated adenoma.Semantic proximity Read ↗

Serrated Colorectal Lesions: An Up-to-Date Review from Histological Pattern to Molecular Pathogenesis.Semantic proximity Read ↗

Pathogenesis and Management of Serrated Polyps: Current Status and Future DirectionsSemantic proximity Read ↗

The serrated pathway to colorectal carcinoma: current concepts and challengesSemantic proximity Read ↗

Evolving pathologic concepts of serrated lesions of the colorectumSemantic proximity Read ↗

Intermediate serrated polyp as an intermediate lesion of hyperplastic polyp and sessile serrated polyp/adenoma in terms of morphological and molecular features.Semantic proximity Read ↗

[Colorectal serrated lesions: current insight on their role in colorectal carcinogenesis].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.