Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Guanine Nucleotide-Binding Protein-Like 1 (GNL1) binds RNA G-quadruplex structures in genes associated with Parkinson's disease.

RNA biology - 1 Sept 2021

Turcotte Marc-Antoine, Garant Jean-Michel, Cossette-Roberge Hélène, Perreault Jean-Pierre

Abstract excerpt

RNAs are highly regulated at the post-transcriptional level in neurodegenerative diseases and just a few mutations can significantly affect the fate of neuronal cells. To date, the impact of G-quadruplex (G4) regulation in neurodegenerative diseases like Parkinson's disease (PD) has not been analysed. In this study, in silico potential G4s located in deregulated genes related to the nervous system were initially...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to G-Quadruplexes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to Neuroblastoma

Share to Parkinson Disease

Share to Tumor Cells, Cultured

Share to Ubiquitin-Protein Ligases

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33305682
DOI: 10.1080/15476286.2020.1847866
PMCID: PMC8354592

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Guanine Nucleotide-Binding Protein-Like 1 (GNL1) binds RNA G-quadruplex structures in genes associated with Parkinson's disease.PMID 33305682Read ↗

5′-UTR G-Quadruplex-Mediated Translation Regulation in Eukaryotes: Current Understanding and Methodological ChallengesSemantic proximity Read ↗

EEF1A1 knock-down regulates the expression and alternative splicing of genes associated with Parkinson`s disease in U251 cellsSemantic proximity Read ↗

RNA G-quadruplexes: emerging mechanisms in disease.Semantic proximity Read ↗

A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease.Semantic proximity Read ↗

RNA binding protein AUF1/HNRNPD regulates nuclear export, stability and translation of SNCA transcriptsSemantic proximity Read ↗

Constitutive translation of human α-synuclein is mediated by the 5′-untranslated regionSemantic proximity Read ↗

FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequencesSemantic proximity Read ↗

The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1Semantic proximity Read ↗

TDP-43 regulates chromatin looping and gene transcription through binding and stabilizing DNA G-quadruplex structuresSemantic proximity Read ↗

Massively parallel characterization of RNA G-quadruplex stability and molecular recognition.Semantic proximity Read ↗

Pathogenic SNPs Affect Both RNA and DNA G-Quadruplexes' Responses to Ligands.Semantic proximity Read ↗

Conjunction of potential G-quadruplex and adjacent cis-elements in the 5' UTR of hepatocyte nuclear factor 4-alpha strongly inhibit protein expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.