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SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression

11 Dec 2020

Abstract excerpt

Human telomerase reverse transcriptase (hTERT) plays an extremely important role in cancer initiation and development, including colorectal cancer (CRC). However, the precise upstream regulatory mechanisms of hTERT in different cancer types remain poorly understood. Here, we uncovered the candidate transcriptional factor of hTERT in CRC and explored its role and the corresponding molecular mechanisms in...

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Share to Cell death mechanisms and regulation
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Share to Telomeres, Telomerase, and Senescence

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PMID: 33305480
DOI: 10.1002/1878-0261.12878

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