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Article

CDC5L Promotes hTERT Expression and Colorectal Tumor Growth

1 Jan 2017

Abstract excerpt

BACKGROUND/AIMS: Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide because the survival rate remains low. Cell division cycle 5-like (CDC5L) is highly expressed in some cancer cells, but the mechanism requires clarification. Human telomerase reverse transcriptase (hTERT) plays important roles in CRC. METHODS: This study aimed to identify a link between CDC5L and hTERT and to...

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PMID: 28472785
DOI: 10.1159/000475916

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