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Article

IL-4Rα deletion disrupts psychomotor performance and reference memory in mice while sparing behavioural phenotype associated with spatial learning.

Brain, behavior, and immunity - 1 Feb 2021

Brombacher T M, Ajonijebu D C, Scibiorek M, Berkiks I, Moses B O, Mpotje T, Brombacher F

Abstract excerpt

Contribution of immune mediators, interleukin-4 and interferon gamma to cognitive functioning is receiving increasing attention. However, the fundamental question about how heterodimeric interleukin-4 receptor alpha- and interferon gamma- producing myeloid cells converge to influence hippocampal-dependent spatial memory tasks through immunomodulation of multisensory inputs from other brain areas remains...

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Identifiers

PMID: 33301870
DOI: 10.1016/j.bbi.2020.12.003
PMCID: PMC7909383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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