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Article

Biomarker alterations associated with distinct patterns of metastatic spread in colorectal cancer.

Virchows Archiv : an international journal of pathology - 1 Apr 2021

Michl M, Taverna F, Kumbrink J, Schiergens T S, Heinemann V, Engel J, Kirchner T, Neumann Jens

Abstract excerpt

Metastatic spread is the most important life-threatening feature of colorectal cancer and is supposed to be mainly driven by alterations in different carcinogenic pathways. The present study compared mutation and expression profiles of distinctive biomarkers in colorectal cancer patients with different clinical metastatic patterns. As for a case-control study, patients were matched according to T category,...

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Identifiers

PMID: 33300106
DOI: 10.1007/s00428-020-02983-6
PMCID: PMC7990752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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