Article
Gene heterogeneity in metastasis of colorectal cancer to the lung.
Seminars in cell & developmental biology - 1 Apr 2017
Hou Jiayun, Zhang Yong, Zhu Zhitu
Abstract excerpt
Colorectal cancer (CRC) as a heterogeneous disease, is one of the most common and serious cancers with high metastases and mortality. Lung is one of the most common sites of CRC metastases with high heterogeneity between cells, pathways, or molecules. The present review will focus on potential roles of gene heterogeneity in KRAS pathway in the development of CRC metastasis to lung and clinical therapies, which...
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