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Genetic mutations in primary malignant melanoma of the esophagus: case report and literature review.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia - 1 Oct 2020

Sanlorenzo Martina, Ribero Simone, Osella Abate Simona, Mariani Sara, Strignano Paolo, Salizzoni Mauro, Savoia Paola, Fierro Maria T, Quaglino Pietro

Abstract excerpt

The most frequent genetic aberrations in mucosal melanoma are activating mutations of c-KIT. Primary malignant melanomas of esophagus (PMME) are uncommon entities, with aggressive biological behavior and poor prognosis. The better definition of their genotype could improve therapeutic options. We report a case of a 66 years old man with a PMME in the lower third of the esophagus. Analysis of c-kit, KRAS, NRAS and...

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PMID: 33295742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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