Article
Rapid and clinically significant response to masitinib in the treatment of mucosal primary esophageal melanoma with somatic KIT exon 11 mutation involving brain metastases: A case report.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Dec 2015
Prosvicova Jarmila, Lukesova Sarka, Kopecky Jindrich, Grim Jiri, Papik Zdenek, Kolarova Renata, Navratilova Blanka, Dubreuil Patrice, Agopian Julie, Mansfield Colin, Moussy Alan, Hermine Olivier
Abstract excerpt
BACKGROUND: Malignant melanoma in the gastrointestinal tract may be primary or metastatic. Mucosal melanoma is a quite rare and aggressive disease, growing hidden and diagnosed with a certain delay which makes treatment difficult. CASE REPORT: The authors present the first patient with c-kit exon 11 mutated primary esophageal melanoma treated with oral tyrosine kinase inhibitor masitinib. A 55-year-old-man...
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