Article
Primary melanoma of the gastrointestinal tract.
World journal of gastroenterology - 28 Feb 2026
De Nardi Paola, Guida Stefania, Damiano Giuseppe, Rizzo Nathalie, Samanes Gajate Ana Maria, Riva Silvia Teresa, Paolino Giovanni, Colombo Michele, Tummineri Roberta, Rongioletti Franco, Mercuri Santo Raffaele, Chiti Arturo, Sileri Pierpaolo, Russo Vincenzo
Abstract excerpt
Primary melanomas of the gastrointestinal tract are rare malignancies, representing less than 2% of all melanomas and 37% of mucosal melanomas. They arise de novo from the mucosal gastrointestinal epithelium, most frequently in the anorectum and esophagus. Their etiology is unclear: Unlike cutaneous melanomas, they are not associated with ultraviolet exposure while genetic predisposition, chronic inflammation,...
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