Article
The CLU gene rs11136000 variant is significantly associated with Alzheimer's disease in Caucasian and Asian populations.
Neuromolecular medicine - 1 Mar 2014
Liu Guiyou, Wang Haiyang, Liu Jiafeng, Li Jingbo, Li Hali, Ma Guoda, Jiang Yongshuai, Chen Zugen, Zhao Bin, Li Keshen
Abstract excerpt
Large-scale genomewide association studies have reported that the CLU rs11136000 polymorphism is significantly associated with Alzheimer's disease (AD) in people of Caucasian ancestry. Recently, this association was investigated in Asian populations (Chinese, Japanese, and Korean). However, these studies reported either a weak association or no association between the rs11136000 polymorphism and AD. We believe...
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