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Article

Extent of polymorphism and selection pressure on the Trypanosoma cruzi vaccine candidate antigen Tc24

20 Jul 2020

Abstract excerpt

Abstract Introduction Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major public health problem in the Americas, and existing drugs have severe limitations. In this context, a vaccine would be an attractive alternative for disease control. One of the difficulties in developing an effective vaccine lies in the high genetic diversity of T. cruzi. In this study, we evaluated the level of...

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PMID: 33294015
DOI: 10.1111/eva.13068

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