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DNA Damaged Induced Cell Death in Oocytes

3 Dec 2020

Abstract excerpt

The production of haploid gametes through meiosis is central to the principle of sexual reproduction. The genetic diversity is further enhanced by exchange of genetic material between homologous chromosomes by the crossover mechanism. This mechanism not only requires correct pairing of homologous chromosomes but also efficient repair of the induced DNA double-strand breaks. Oocytes have evolved a unique quality...

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PMID: 33287328
DOI: 10.3390/molecules25235714

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