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Article

The DNA damage response in mammalian oocytes

1 Jan 2013

Abstract excerpt

DNA damage is one of the most common insults that challenge all cells. To cope, an elaborate molecular and cellular response has evolved to sense, respond to and correct the damage. This allows the maintenance of DNA fidelity essential for normal cell viability and the prevention of genomic instability that can lead to tumor formation. In the context of oocytes, the impact of DNA damage is not one of tumor...

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Identifiers

PMID: 23805152
DOI: 10.3389/fgene.2013.00117

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