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Article

Effect of BRCA1 haplotype on survival of non-small-cell lung cancer patients treated with platinum-based chemotherapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Dec 2008

Kim Hong-Tae, Lee Jong-Eun, Shin Eun-Soon, Yoo Yeon-Kyeong, Cho Jae-Hwa, Yun Min-Hye, Kim Yeul-Hong, Kim Se-Kyu, Kim Hyun-Jung, Jang Tae-Won, Kwak Seung-Min, Kim Chul-Soo, Ryu Jeong-Seon

Abstract excerpt

PURPOSE: To determine whether germ-line variations in BRCA1 affect outcome in non-small-cell lung cancer (NSCLC) patients treated with platinum combination chemotherapy. PATIENTS AND METHODS: We evaluated the associations of four tagging BRCA1 polymorphisms and their haplotypes with treatment outcome in 300 NSCLC patients at stages IIIA (16%), IIIB (31%), and IV (53%). RESULTS: The median age was 63 years (range,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19018088
DOI: 10.1200/JCO.2008.16.6496

Genes

BRCA1
GATC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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