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Article

In silico mutagenesis of human ACE2 with S protein and translational efficiency explain SARS-CoV-2 infectivity in different species.

PLoS computational biology - 1 Dec 2020

Delgado Blanco Javier, Hernandez-Alias Xavier, Cianferoni Damiano, Serrano Luis

Abstract excerpt

The coronavirus disease COVID-19 constitutes the most severe pandemic of the last decades having caused more than 1 million deaths worldwide. The SARS-CoV-2 virus recognizes the angiotensin converting enzyme 2 (ACE2) on the surface of human cells through its spike protein. It has been reported that the coronavirus can mildly infect cats, and ferrets, and perhaps dogs while not pigs, mice, chicken and ducks....

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Identifiers

PMID: 33284795
DOI: 10.1371/journal.pcbi.1008450
PMCID: PMC7746295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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