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Article

Importance of two PDZ domains for the proteolytic and chaperone activities of Helicobacter pylori serine protease HtrA.

Cellular microbiology - 1 Apr 2021

Zarzecka Urszula, Matkowska Dorota, Backert Steffen, Skorko-Glonek Joanna

Abstract excerpt

The Helicobacter pylori HtrA protein (HtrAHp ) is an important virulence factor involved in the infection process by proteolysis of components of the tight (claudin-8 and occludin) and adherens junctions (E-cadherin) between epithelial cells. As a protease and chaperone, HtrAHp is involved in protein quality control, which is particularly important under stress conditions. HtrAHp contains a protease domain and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33277762
DOI: 10.1111/cmi.13299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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