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Article

Effects of Thyroid Status on Regional Brain Volumes: A Diagnostic and Genetic Imaging Study in UK Biobank.

The Journal of clinical endocrinology and metabolism - 8 Mar 2021

Chambers Tom, Anney Richard, Taylor Peter N, Teumer Alexander, Peeters Robin P, Medici Marco, Caseras Xavier, Rees D Aled

Abstract excerpt

BACKGROUND: Thyroid hormone is essential for optimal human neurodevelopment and may modify the risk of attention-deficit/hyperactivity disorder (ADHD). However, the brain structures involved are unknown and it is unclear if the adult brain is also susceptible to changes in thyroid status. METHODS: We used International Classification of Disease-10 codes, polygenic thyroid scores at different thresholds of...

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Identifiers

PMID: 33274371
DOI: 10.1210/clinem/dgaa903
PMCID: PMC7947746

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