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Genome-Wide Meta-Analysis Identifies 47 Novel Loci and Links Essential Tremor to Ventral Diencephalon and Cerebellum Morphometry

2025-11-11

Abstract excerpt

<h4>ABSTRACT</h4> Essential tremor (ET) is the most common movement disorder, yet its genetic basis remains poorly understood. We performed a genome-wide association meta-analysis including 20,268 ET cases and 723,761 neurologically healthy controls of European ancestry from the Million Veteran Program, 23andMe Research Institute and All of Us. We identified 50 independent genome-wide significant loci, including...

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Literature Corpus work
68a4fe60-a685-546b-9c34-aaf425da6ba2
DOI
10.1101/2025.11.10.25339873
Open publication

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Genome-Wide Meta-Analysis Identifies 47 Novel Loci and Links Essential Tremor to Ventral Diencephalon and Cerebellum MorphometryDOI 10.1101/2025.11.10.25339873
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