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Genome-wide association study of human pineal gland volume as proxy for melatonin secretion

2025-03-11

Abstract excerpt

The pineal gland is the primary source of melatonin synthesis and secretion. Reduced pineal gland volume results in lower melatonin levels and has been linked to sleep impairment, as well as many (age-related) metabolic and neurodegenerative disorders. However, its genetic architecture remains unknown. Using brain imaging and genotype data from the UK Biobank (N=38,254) and Rhineland Study (N=5,286), we conducted...

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Literature Corpus work
125fd6e3-a5b3-5783-a734-faeab88d2387
DOI
10.1101/2025.03.10.25323654
Open publication

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Genome-wide association study of human pineal gland volume as proxy for melatonin secretionDOI 10.1101/2025.03.10.25323654
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