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Unraveling the activation process and core driver genes of HSCs during cirrhosis by single-cell transcriptome

1 Aug 2023

Abstract excerpt

Worldwide, cirrhosis is a common cause of death, manifesting itself as fibrosis of the liver tissue. When the liver is damaged, the liver produces fibrotic, proliferative myofibroblasts, which are formed by the differentiation of activated hepatic stellate cells. There are no effective antifibrotic treatment options. To deeply explore the activation process of hepatic stellate cells (HSCs) and to discover better...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37674431
DOI: 10.1177/15353702231191109

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