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Stable high frequencies of sulfadoxine-pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine-pyrimethamine in Ujjain, Madhya Pradesh, India

2020-06-03

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<title>Abstract</title> <p><bold>Background </bold>Artesunate plus sulfadoxine-pyrimethamine (ASP) is first-line treatment for uncomplicated <italic>Plasmodium falciparum</italic> malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central India, the frequency of mutations associated with increased drug tolerance, but not overt resistance to sulfado...

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Literature Corpus work
616d9cfe-802d-5579-881c-c64809fa660e
DOI
10.21203/rs.2.21394/v3
Open publication

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Stable high frequencies of sulfadoxine-pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine-pyrimethamine in Ujjain, Madhya Pradesh, IndiaDOI 10.21203/rs.2.21394/v3
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