Article
A novel viable allele of Arabidopsis CULLIN1 identified in a screen for superroot2 suppressors by next generation sequencing-assisted mapping.
PloS one - 1 Jan 2014
Pacurar Daniel I, Pacurar Monica L, Pacurar Andrea M, Gutierrez Laurent, Bellini Catherine
Abstract excerpt
Map-based cloning (MBC) is the conventional approach for linking phenotypes to genotypes, and has been successfully used to identify causal mutations in diverse organisms. Next-generation sequencing (NGS) technologies offer unprecedented possibilities to sequence the entire genomes of organisms, thereby in principle enabling direct identification of causal mutations without mapping. However, although...
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