Evaluation of the Association of rs4680 COMT Polymorphism and Clinical Parameters of the Tumor in Colorectal Cancer (a Pilot Study).

doi:10.1007/s10517-020-05046-7

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Article

Evaluation of the Association of rs4680 COMT Polymorphism and Clinical Parameters of the Tumor in Colorectal Cancer (a Pilot Study).

Bulletin of experimental biology and medicine - 1 Dec 2020

Ivanova T I, Potapov A L, Zemskova D V, Khorokhorina V A, Shegai P V, Ivanov S A, Kaprin A D

Abstract excerpt

We analyzed association of rs4680 polymorphism of catechol-O-methyltransferase (COMT) gene with clinical parameters of the tumor in patients with colorectal cancer (n=100). Based on the classification of the tumor according to the TNM system, groups were formed taking into account the size and spreading of the primary tumor (T1+T2 vs Т3+Т4) and the presence of regional (N0 vs N1) and distant metastases (M0 vs...

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PMID: 33263843
DOI: 10.1007/s10517-020-05046-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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