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Article

Interaction between vitamin E intake and a COMT gene variant on colorectal cancer risk among Korean adults: a case-control study.

Epidemiology and health - 1 Jan 2023

Jun Shinyoung, Gunathilake Madhawa, Lee Jeonghee, Oh Jae Hwan, Chang Hee Jin, Sohn Dae Kyung, Shin Aesun, Kim Jeongseon

Abstract excerpt

OBJECTIVES: Previous human trials have not supported the anticarcinogenic effect of vitamin E despite biological plausibility and considerable epidemiological evidence. A possible explanation for this inconsistency is the interactive effect of the catechol-O-methyltransferase (COMT) gene and supplemental vitamin E on cancer. We examined whether a COMT gene variant modulates the effect of dietary vitamin E intake...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37974041
DOI: 10.4178/epih.e2023100
PMCID: PMC10876447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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